SAPHO syndrome associated with acne conglobata successfully treated with etanercept

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Severe acne successfully treated with etanercept.

Sir, Effective systemic treatments for severe acne vulgaris, such as oral antibiotics, oral isotretinoin and anti-androgens, are often associated with undesirable side-effects or are limited to a selected patient population. Furthermore, some patients with severe acne fail to respond to these therapies (1). Etanercept, a dimeric fusion protein linking part of the human p75 tumour necrosis facto...

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SAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate.

SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare chronic inflammatory musculoskeletal disorder of unknown etiology observed in children and young adults, which involves both osteo-articular inflammation and skin abnormalities. We review the case of a 22-year-old male, who presented with a 5-year history of hidradenitis suppurativa (HS), acne vulgaris, joint sti...

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SAPHO syndrome treated with pamidronate.

A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium. A diagnosis of SAPHO syndrome was made and he was treated with IV pamidronate. His pain reduced and acne completely cleared up on therapy. A dermatologist has rarely made a diagnosis of SAP...

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Interstitial granulomatous dermatitis successfully treated with etanercept

PATIENT Female, 51 FINAL DIAGNOSIS: Interstitial Granulomatous Dermatitis Symptoms: Joint pain • pruritic rush MEDICATION Etanercept Clinical Procedure: - Specialty: Rheumatology. OBJECTIVE Rare disease. BACKGROUND Interstitial granulomatous disease (IGD) is a rare skin condition that presents with erythematous and violaceous plaques, and may be associated with pruritus and pain. The caus...

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Multicentric Reticulohistiocytosis Treated Successfully with Etanercept

Multicentric reticulohistiocytosis (MRH) is an uncommon systemic disease of unknown aetiology, which is characterized by the presence of papulonodular lesions, and is caused by the proliferation of histiocytes associated with arthritis. There are only just 200 cases described in the scientific literature. It can behave like a paraneoplasia and may be malignant in a quarter of the patients. We w...

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ژورنال

عنوان ژورنال: Journal of the Formosan Medical Association

سال: 2015

ISSN: 0929-6646

DOI: 10.1016/j.jfma.2013.10.001